Nocturnin Suppresses Igf1 Expression in Bone by Targeting the 3′ Untranslated Region of Igf1 mRNA
نویسندگان
چکیده
منابع مشابه
A 3'-untranslated region polymorphism in IGF1 predicts survival of non-small cell lung cancer in a Chinese population.
PURPOSE Disruption of the balance of insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP3) has been implicated in the etiology and progression of lung and other cancers. Single nucleotide polymorphisms (SNP) in IGF1 and IGFBP3 have been reported to be associated with the expression of the IGF-I/IGFBP3 axis. Therefore, we hypothesized that SNPs in these two genes were associate...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2010
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2010-0407